Bioactivity | 11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs[1]. |
Invitro | 11-Deoxy prostaglandin E1 (100 μg/mL ) 对 Carbachol (1 μg/kg) 诱导收缩的离体豚鼠气管条表现出松弛的作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 11-Deoxy prostaglandin E1 相关抗体: |
In Vivo | 11-Deoxy prostaglandin E1 (喷雾给药) 对豚鼠和猫没有显著的支气管扩张剂效果[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 37786-00-8 |
Formula | C20H34O4 |
Molar Mass | 338.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Greenberg R, et al. The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578). Can J Physiol Pharmacol. 1975 Oct;53(5):799-809. |