| Bioactivity | 1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2]. |
| Name | 1-Oxo Ibuprofen |
| CAS | 65813-55-0 |
| Formula | C13H16O3 |
| Molar Mass | 220.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. YongFang Rao, et al. Degradation of ibuprofen by a synergistic UV/Fe(III)/Oxone process. Chemical Engineering Journal. Volume 283, 1 January 2016, Pages 65-75. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. |
1-Oxo Ibuprofen
CAS: 65813-55-0 F: C13H16O3 W: 220.26
1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen
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