| Bioactivity | 1-Naphthyl 3,5-dinitrobenzoate is a potent 5-lipoxygenase inhibitor with IC50 values of 1.04 µM and 3.6 µM for 5-LOX and mPGES-1, respectively. 1-Naphthyl 3,5-dinitrobenzoate has strong inhibition activity in the human whole blood (HWB) assay with an IC50 value of 8.6 μM. 1-Naphthyl 3,5-dinitrobenzoate can be used in research of inflammation[1]. |
| Name | 1-Naphthyl 3,5-dinitrobenzoate |
| CAS | 93261-39-3 |
| Formula | C17H10N2O6 |
| Molar Mass | 338.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wu Y, et, al. Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors. J Med Chem. 2012 Mar 22;55(6):2597-605. |
1-Naphthyl 3,5-dinitrobenzoate
CAS: 93261-39-3 F: C17H10N2O6 W: 338.27
1-Naphthyl 3,5-dinitrobenzoate is a potent 5-lipoxygenase inhibitor with IC50 values of 1.04 µM and 3.6 µM for 5-LOX a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.