| Bioactivity | 1-Methyladenosine (Standard) is the analytical standard of 1-Methyladenosine. This product is intended for research and analytical applications. 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.In Vitro:Compared to surrounding tumor tissues, 1-methyladenosine methylation in RNA is aberrantly elevated in hepatocellular carcinoma (HCC) cell lines and liver cancer stem cells (CSCs). Methylated 1-methyladenosine can promote cholesterol synthesis and activate the Hedgehog signaling pathway by enhancing the translation of PPARδ in liver CSCs, ultimately driving the self-renewal and tumorigenesis of liver cancer stem cells. |
| CAS | 15763-06-1 |
| Formula | C11H15N5O4 |
| Molar Mass | 281.27 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
1-Methyladenosine (Standard)
CAS: 15763-06-1 F: C11H15N5O4 W: 281.27
1-Methyladenosine (Standard) is the analytical standard of 1-Methyladenosine. This product is intended for research and
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This product is for research use only, not for human use. We do not sell to patients.