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1'-Hydroxy bufuralol

CAS: 57704-16-2 F: C16H23NO3 W: 277.36

1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity.
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Bioactivity 1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1].
Name 1'-Hydroxy bufuralol
CAS 57704-16-2
Formula C16H23NO3
Molar Mass 277.36
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reference [1]. Evangelos P Daskalopoulos, et al. D₂-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Mol Pharmacol. 2012 Oct;82(4):668-78. [2]. H Yamazaki, et al. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77.