Bioactivity | 1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377)[1]. |
In Vivo | 应用 44 nmol 1-Ethenylpyrene (1-Vinylpyrene) 可抑制 10 nmol DMBA 约 30% 的肿瘤发生;应用 4.4 μmol 1-Ethenylpyrene (1-Vinylpyrene) 可抑制 200 nmol Benzo[a]pyrene 的肿瘤起始,抑制率约为 56%[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 17088-21-0 |
Formula | C18H12 |
Molar Mass | 228.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. W L Alworth, et al. Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene initiated skin tumors. Carcinogenesis. 1991 Jul;12(7):1209-15. |