Bioactivity | 1-Benzyl-APDC acts as an agonist for mGluR6 in CHO cells, with an EC50 of 20 μM. 1-Benzyl-APDC is a weak antagonist of mGluR2, with an IC50 of 200 μM[1]. |
CAS | 171336-76-8 |
Formula | C13H16N2O4 |
Molar Mass | 264.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. J K Mukhopadhyaya, et al. Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1919-24. |