| Bioactivity | 1-(Isothiazol-3-yl)ethan-1-one (Q11) is a CYP2E1 inhibitor. 1-(Isothiazol-3-yl)ethan-1-one can be used in rheumatoid arthritis and sepsis related research[1]. | ||||||||||||
| CAS | 88511-35-7 | ||||||||||||
| Formula | C5H5NOS | ||||||||||||
| Molar Mass | 127.16 | ||||||||||||
| Appearance | 液体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Han Z,et al. Discovery of CYP2E1 as a novel target in rheumatoid arthritis and validation by a new specific CYP2E1 inhibitor. Biochem Pharmacol. 2024 Aug 20;229:116501. [2]. Gao N, et al. The CYP2E1 inhibitor Q11 ameliorates LPS-induced sepsis in mice by suppressing oxidative stress and NLRP3 activation. Biochem Pharmacol. 2023 Aug;214:115638. |
1-(Isothiazol-3-yl)ethan-1-one
CAS: 88511-35-7 F: C5H5NOS W: 127.16
1-(Isothiazol-3-yl)ethan-1-one (Q11) is a CYP2E1 inhibitor. 1-(Isothiazol-3-yl)ethan-1-one can be used in rheumatoid art
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