| Bioactivity | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2]. | |||||||||
| Invitro | In empty lipid nanoparticle (LNP) systems that do not contain siRNA, DSPC-cholesterol resides in outer layers, whereas in loaded systems a portion of the DSPC-cholesterol is internalised together with siRNA[2]. | |||||||||
| Name | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine | |||||||||
| CAS | 816-94-4 | |||||||||
| Formula | C44H88NO8P | |||||||||
| Molar Mass | 790.15 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
|||||||||
| Reference | [1]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [2]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739. |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
CAS: 816-94-4 F: C44H88NO8P W: 790.15
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.