Bioactivity | 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells[1]. |
Invitro | 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) 以浓度依赖性方式(1-100 μM)降低 NCI-H28 细胞活力,但对 Met5A(非恶性间皮细胞)没有影响细胞[1]。1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 100 μM; 10-60 minutes) 倾向于减弱 ERK1/ERK2 的活性[1]。1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 30-100 μM; 48 hours) 显著增加 TUNEL 阳性 NCI-H28 细胞,表明细胞凋亡,对 Met5A 的影响最小[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 相关抗体: Cell Viability Assay[1] Cell Line: |
CAS | 61599-23-3 |
Formula | C37H70NO8P |
Molar Mass | 687.93 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kaku Y, et al. Dipalmitoleoyl-phosphatidylethanolamine induces apoptosis of NCI-H28 malignant mesothelioma cells. Anticancer Res. 2014 Apr;34(4):1759-64. |