| Bioactivity | 1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research[1][2][3][4]. | ||||||||||||
| CAS | 10465-81-3 | ||||||||||||
| Formula | C12H20N4O2 | ||||||||||||
| Molar Mass | 252.31 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Tsunoda T, et al. 1, 1′-(azodicarbonyl) dipiperidine-tributylphosphine, a new reagent system for mitsunobu reaction[J]. Tetrahedron letters, 1993, 34(10): 1639-1642. [2]. Hirose D, et al. Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents. J Org Chem. 2018 Apr 20;83(8):4712-4729. [3]. Zhang X, et al. Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3272-3278. [4]. Mogensen JP, et al. Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template. Bioorg Med Chem Lett. 2003 Jan 20;13(2):257-60. |
1,1'-(Azodicarbonyl)-dipiperidine
CAS: 10465-81-3 F: C12H20N4O2 W: 252.31
1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1
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