Bioactivity | (αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, is a cytotoxic agent. (αR)-Cyclopropaneacetamide-Exatecan inhibits U87MG and SK-BR-3 cells proliferation, with IC50s of 8.11 and 2.31 μM[1]. | ||||||||||||
Name | (αR)-Cyclopropaneacetamide-Exatecan | ||||||||||||
CAS | 2414254-37-6 | ||||||||||||
Formula | C29H28FN3O6 | ||||||||||||
Molar Mass | 533.55 | ||||||||||||
Appearance | 固体 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Haiqing H, et, al. Antibody-drug conjugate and medical use thereof. WO2021190564A1. |