(±)-threo-3-Methylglutamic acid_product_DataBase

Bioactivity	(±)-threo-3-Methylglutamic acid is a potent EAAT2/4 inhibitor. (±)-threo-3-Methylglutamic acid also is an ionotropic glutamate receptor agonist. (±)-threo-3-Methylglutamic acid inhibits glutamate uptake by rod outer segments[1][2].
Invitro	(±)-threo-3-Methylglutamic acid (0-300 µM) 以浓度依赖性方式抑制视杆外节对谷氨酸的摄取，IC50 值为 38.35 µM[2]。
Name	(±)-threo-3-Methylglutamic acid
CAS	63088-04-0
Formula	C6H11NO4
Molar Mass	161.16
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Eliasof S, et al. Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems. J Neurochem. 2001 Apr;77(2):550-7. [2]. Pignataro L, et al. Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors. Mol Cell Neurosci. 2005 Mar;28(3):440-51.

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