| Bioactivity | (±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice[1]. |
| In Vivo | (±)-Pantothenic acid (3 × 200 mg/kg; IP, single dosage) blocks VPA-induced decreases in c-Myb and Pim-1 protein expression; reduces the incidence of NTD to 6.8% in VPA-injected CD-1 mice, while incidence of the untreated group is 23.6%[1]. |
| Name | (±)-Pantothenic acid |
| CAS | 599-54-2 |
| Formula | C9H17NO5 |
| Molar Mass | 219.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tahiliani AG, Beinlich CJ. Pantothenic acid in health and disease. Vitam Horm. 1991;46:165-228. [2]. Dawson JE, et al. Folic acid and pantothenic acid protection against valproic acid-induced neural tube defects in CD-1 mice. Toxicol Appl Pharmacol. 2006 Mar 1;211(2):124-32. |
(±)-Pantothenic acid
CAS: 599-54-2 F: C9H17NO5 W: 219.23
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzym
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