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(±)-Naproxen-13C,d3

CAS: 1261392-52-2 F: C1313CH11D3O3 W: 234.27

(±)-Naproxen-13C,d3 is the deuterium and 13C labeled (±)-Naproxen. (±)-Naproxen ((Rac)-Naproxen) is a racemate of Nap
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity (±)-Naproxen-13C,d3 is the deuterium and 13C labeled (±)-Naproxen[1]. (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name (±)-Naproxen-13C,d3
CAS 1261392-52-2
Formula C1313CH11D3O3
Molar Mass 234.27
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.