Bioactivity | (rac)-Streptonigrin ((rac)-Bruneomycin) is the racemic form of Streptonigrin. Streptonigrin (HY-124586) is a natural product produced by the actinobacterium Streptomyces flocculus, exhibiting antitumor and antibacterial activities. Streptonigrin can act as a pan-PAD inhibitor, with IC50 values of 48.3 μM, 26.1 μM, 0.43 μM, and 2.5 μM for PAD1, PAD2, PAD3, and PAD4, respectively[1]. |
CAS | 1079893-79-0 |
Formula | C25H22N4O8 |
Molar Mass | 506.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Dreyton CJ, et al. Insights into the mechanism of Streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem. 2014 Feb 15;22(4):1362-9. |