PeptideDB

(aS)-PH-797804

CAS: 1358027-80-1 F: C22H19BrF2N2O3 W: 477.30

(aS)-PH-797804 is a selective p38 MAPK inhibitor with IC50 values for p38 α /β of 26 and 102 nM, respectively. (aS)-PH
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Bioactivity (aS)-PH-797804 is a selective p38 MAPK inhibitor with IC50 values for p38 α /β of 26 and 102 nM, respectively. (aS)-PH-797804 has anti-inflammatory activity[1][2].
Name (aS)-PH-797804
CAS 1358027-80-1
Formula C22H19BrF2N2O3
Molar Mass 477.30
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Hope HR, et al. Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation. J Pharmacol Exp Ther. 2009 Dec;331(3):882-95. [2]. Selness SR, et al. Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4066-71.