| Bioactivity | (Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1]. | ||||||||||||
| Name | (Z)-SU5614 | ||||||||||||
| CAS | 1055412-47-9 | ||||||||||||
| Formula | C15H13ClN2O | ||||||||||||
| Molar Mass | 272.73 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Spiekermann K, et al. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood. 2003 Feb 15;101(4):1494-504. |
(Z)-SU5614
CAS: 1055412-47-9 F: C15H13ClN2O W: 272.73
(Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 a
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