Bioactivity | (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1]. |
Name | (Z)-Pitavastatin calcium |
CAS | 1159588-21-2 |
Formula | C25H24FNO4.1/2Ca |
Molar Mass | 440.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215. |