| Bioactivity | (Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis[1]. | ||||||||||||
| Invitro | JIB-04 inhibits the demethylase activity of Jumonji enzymes in vitro and in cells, without affecting other α-ketoglutarate dependent hydroxylases or histone modifying enzymes [1]. | ||||||||||||
| Name | (Z)-JIB-04 | ||||||||||||
| CAS | 199596-24-2 | ||||||||||||
| Formula | C17H13ClN4 | ||||||||||||
| Molar Mass | 308.76 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Wang L, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013;4:2035. |
(Z)-JIB-04
CAS: 199596-24-2 F: C17H13ClN4 W: 308.76
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive
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