| Bioactivity | (Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1]. |
| Name | (Z)-GW 5074 |
| CAS | 1233748-60-1 |
| Formula | C15H8Br2INO2 |
| Molar Mass | 520.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30. |
(Z)-GW 5074
CAS: 1233748-60-1 F: C15H8Br2INO2 W: 520.94
(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the w
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