| Bioactivity | (Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β[1]. |
| Invitro | (Sar1,Ile4,8)-Angiotensin II (30 μM；30 分钟) 增加肝细胞中胰岛素刺激的 Akt 和 GSK3α/β 磷酸化的表达[1]。 |
| Name | (Sar1,Ile4,8)-Angiotensin II |
| CAS | 185461-45-4 |
| Sequence | {Sar}-Arg-Val-Ile-Ile-His-Pro-Ile |
| Shortening | {Sar}-RVIIHPI |
| Formula | C43H75N13O9 |
| Molar Mass | 918.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
(Sar1,Ile4,8)-Angiotensin II
CAS: 185461-45-4 F: C43H75N13O9 W: 918.14
(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-An
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