(S,S)-TAPI-1_product_DataBase

CAS: 171235-71-5 F: C26H37N5O5 W: 499.60

(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor[1][2].

Target

TACE (ADAM17), MMP

Name

(S,S)-TAPI-1

CAS

171235-71-5

Formula

C26H37N5O5

Molar Mass

499.60

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Bae EH, et al. Tumor necrosis factor α-converting enzyme inhibitor attenuates lipopolysaccharide-induced reactive oxygen species and mitogen-activated protein kinase expression in human renal proximal tubule epithelial cells. Korean J Physiol Pharmacol. 2 [2]. Moss ML, et al. Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation. Mediators Inflamm. 2017;2017:9673537.

PeptideDB

(S,S)-TAPI-1

CAS: 171235-71-5 F: C26H37N5O5 W: 499.60