Bioactivity | (S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R)-ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor[1]. | ||||||||||||
Invitro | (S)-ZINC-3573 displays no activity on MRGPRX2 at concentrations below 100 μM[1]. | ||||||||||||
In Vivo | (R)-ZINC-3573阴性对照 | ||||||||||||
Name | (S)-ZINC-3573 | ||||||||||||
CAS | 2095596-11-3 | ||||||||||||
Formula | C18H21N5 | ||||||||||||
Molar Mass | 307.39 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Katherine Lansu, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536. |