PeptideDB

(S)-ZINC-3573

CAS: 2095596-11-3 F: C18H21N5 W: 307.39

(S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R
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Bioactivity (S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R)-ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor[1].
Invitro (S)-ZINC-3573 displays no activity on MRGPRX2 at concentrations below 100 μM[1].
In Vivo (R)-ZINC-3573阴性对照
Name (S)-ZINC-3573
CAS 2095596-11-3
Formula C18H21N5
Molar Mass 307.39
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Katherine Lansu, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536.