Bioactivity | (S)-Trichostatin A ((S)-TSA) 是一种 HDAC6 选择性抑制剂,对斑马鱼 HDAC6 和人 HDAC6 的 IC50 值分别为 9.88 nM和 11.1 nM。(S)-Trichostatin A 弱抑制其他人 HDAC。 |
Name | (S)-Trichostatin A |
CAS | 122292-85-7 |
Formula | C17H22N2O3 |
Molar Mass | 302.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yasuyuki Miyake, et al. Structural insights into HDAC6 tubulin deacetylation and its selective inhibition. Nat Chem Biol. 2016 Sep;12(9):748-54. |