| Bioactivity | (S)-SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant drug[1][2]. | ||||||||||||
| Target | IC50: 5 μM (hGAT-3), 21 μM (rGAT-2). | ||||||||||||
| Name | (S)-SNAP5114 | ||||||||||||
| CAS | 157604-55-2 | ||||||||||||
| Formula | C30H35NO6 | ||||||||||||
| Molar Mass | 505.60 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Borden LA, et al. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site. Receptors Channels. 1994;2(3):207-13. [2]. Borden LA, et al. GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem Int. 1996 Oct;29(4):335-56. |
(S)-SNAP5114
CAS: 157604-55-2 F: C30H35NO6 W: 505.60
(S)-SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respec
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