Bioactivity | (S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 (example 39) is a PERK inhibitor, with an IC50 of 0.101-0.250 μM[1][2]. |
Name | (S)-PERK-IN-5 |
CAS | 2616821-92-0 |
Formula | C25H26F2N4O3 |
Molar Mass | 468.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Calvo V, et al. Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors. Bioorg Med Chem Lett. 2021;43:128058. [2]. Alan C. Rigby, et al. Perk inhibitors for treating viral infections. WO2021231782A1. |