| Bioactivity | (S)-HexylHIBO is the S-enantiomer of HexylHIBO. HexylHIBO is a group I mGluR antagonist. HexylHIBO elevates the hypothalamus-pituitary-adrenal axis response to restraint in rats. HexylHIBO is promising for research of central nervous system-related diseases[1][2]. |
| CAS | 334887-48-8 |
| Formula | C12H20N2O4 |
| Molar Mass | 256.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Evanson NK, et al. Metabotropic glutamate receptor-mediated signaling dampens the HPA axis response to restraint stress. Physiol Behav. 2015 Oct 15;150:2-7. [2]. Madsen U, et al. 4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes. Neuropharmacology. 2005;49 Suppl 1:114-9. |
(S)-HexylHIBO
CAS: 334887-48-8 F: C12H20N2O4 W: 256.30
(S)-HexylHIBO is the S-enantiomer of HexylHIBO. HexylHIBO is a group I mGluR antagonist. HexylHIBO elevates the hypothal
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