| Bioactivity | (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2]. | ||||||||||||
| Name | (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate | ||||||||||||
| CAS | 2414393-48-7 | ||||||||||||
| Formula | C12H14O3 | ||||||||||||
| Molar Mass | 206.24 | ||||||||||||
| Appearance | 液体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Li Zhen, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1. 2023-02-23. [2]. Huang Q, et al. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents. Eur J Med Chem. 2013;63:746-757. |
(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate
CAS: 2414393-48-7 F: C12H14O3 W: 206.24
(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Campt
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