(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate_product_DataBase

CAS: 2414393-48-7 F: C12H14O3 W: 206.24

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Campt

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].

Name

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

CAS

2414393-48-7

Formula

C12H14O3

Molar Mass

206.24

Appearance

液体

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Li Zhen, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1. 2023-02-23. [2]. Huang Q, et al. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents. Eur J Med Chem. 2013;63:746-757.

PeptideDB

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

CAS: 2414393-48-7 F: C12H14O3 W: 206.24