Bioactivity | (S)-2-Amino-3,3-dimethylbutanoic acid-18O, d2 is a deuterated labeled (S)-2-Amino-3,3-dimethylbutanoic acid[1]. (S)-2-amino-3,3-dimethylbutanoic acid is a leucine derivative[2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (S)-2-Amino-3,3-dimethylbutanoic acid-18O, d2 相关抗体: |
Formula | C8H15D2NO18O |
Molar Mass | 163.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. |