Bioactivity | (S)-(+)-Modafinic acid-d5 is deuterium labeled (S)-(+)-Modafinic acid. |
Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
Name | (S)-(+)-Modafinic acid-d5 |
Formula | C15H9D5O3S |
Molar Mass | 279.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Ke-hua Wu, et al. Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China. Acta Pharmacologica Sinica (2012) 33: 1401–1408. |