| Bioactivity | (Rac)-XL177A is the racemic isomer of XL177A (HY-138794). XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. XL177A elicits cancer cell-killing effects through a p53-dependent mechanism[1]. | ||||||||||||
| CAS | 2417089-73-5 | ||||||||||||
| Formula | C48H57ClN8O5 | ||||||||||||
| Molar Mass | 861.47 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Schauer N J, et al. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism[J]. Scientific reports, 2020, 10(1): 5324. |
(Rac)-XL177A
CAS: 2417089-73-5 F: C48H57ClN8O5 W: 861.47
(Rac)-XL177A is the racemic isomer of XL177A (HY-138794). XL177A is a highly potent and selective irreversible USP7 inhi
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