| Bioactivity | (Rac)-SAR131675 is the racemate of SAR131675. SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM[1][2]. |
| Invitro | SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM[1][2]. |
| Name | (Rac)-SAR131675 |
| CAS | 1092539-44-0 |
| Formula | C18H22N4O4 |
| Molar Mass | 358.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mitroshina EV, et al. Neuroprotective Effect of Kinase Inhibition in Ischemic Factor Modeling In Vitro. Int J Mol Sci. 2021;22(4):1885. [2]. Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49. |
(Rac)-SAR131675
CAS: 1092539-44-0 F: C18H22N4O4 W: 358.39
(Rac)-SAR131675 is the racemate of SAR131675. SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM
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