| Bioactivity | (Rac)-S 16924 is a partial agonist of the 5-HT1A receptor. (Rac)-S 16924 regulates signaling through its interaction with the 5-HT1A receptor, and (Rac)-S 16924 can stabilize the receptor in its G-protein-coupled conformation without fully activating it, which may affect intracellular signaling pathways associated with this receptor. (Rac)-S 16924 can be used to study the 5-HT1A receptor in mental disorders, especially schizophrenia[1]. |
| CAS | 734513-52-1 |
| Formula | C22H24FNO4 |
| Molar Mass | 385.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Newman-Tancredi A, et al. Efficacy of antipsychotic agents at human 5-HT1A receptors determined by [3H] WAY100, 635 binding affinity ratios: relationship to efficacy for G-protein activation[J]. European journal of pharmacology, 2001, 428(2): 177-184. |
(Rac)-S 16924
CAS: 734513-52-1 F: C22H24FNO4 W: 385.43
(Rac)-S 16924 is a partial agonist of the 5-HT1A receptor. (Rac)-S 16924 regulates signaling through its interaction wit
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