Bioactivity | (Rac)-Idroxioleic acid (2-Hydroxyoleic acid) sodium is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid sodium has anti-tumor effect[1]. |
Invitro | (Rac)-Idroxioleic acid sodium (25-75 μM, 72 小时) 以时间和浓度依赖性的方式损害 Jurkat 细胞的生长,IC50 值约 40 μM[1].(Rac)-Idroxioleic acid sodium (25-50 μM, 72 小时) 也能显著且浓度依赖性地增加 PARP 的蛋白酶切割,这是一个细胞凋亡的分子标记[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (Rac)-Idroxioleic acid sodium 相关抗体: Cell Viability Assay[1] Cell Line: |
In Vivo | (Rac)-Idroxioleic acid sodium 显著且明显地抑制了感染 Jurkat 细胞的小鼠肿瘤生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 1229114-68-4 |
Formula | C18H33NaO3 |
Molar Mass | 320.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Llado V, et al. Minerval induces apoptosis in Jurkat and other cancer cells. J Cell Mol Med. 2010 Mar;14(3):659-70. |