| Bioactivity | (Rac)-GSK-3484862 is the inactive isomer of GSK-3484862 (HY-135146), and can be used as an experimental control. GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity[1][2]. | ||||||||||||
| Name | (Rac)-GSK-3484862 | ||||||||||||
| CAS | 2170136-02-2 | ||||||||||||
| Formula | C19H19N5OS | ||||||||||||
| Molar Mass | 365.45 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Nathalia Azevedo Portilho, et al. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. [2]. Keystone Symposia 2019 - Epigenetics and Human Disease |
(Rac)-GSK-3484862
CAS: 2170136-02-2 F: C19H19N5OS W: 365.45
(Rac)-GSK-3484862 is the inactive isomer of GSK-3484862 (HY-135146), and can be used as an experimental control. GSK-348
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