Bioactivity | (Rac)-Deox B 7,4, a homoisoflavanoid compound, inhibits microtubule polymerization via binding near the colchicine site and promote reversible G2 arrest. (Rac)-Deox B 7,4 possesses nanomolar anti-leukemic activity[1]. |
Invitro | (Rac)-Deox B 7,4 可降低多种AML细胞系的生长和活力 (IC50 值范围 324-556 nM)。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (Rac)-Deox B 7,4 相关抗体: |
CAS | 674786-37-9 |
Formula | C18H18O5 |
Molar Mass | 314.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Dannie Bernard, et al. Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis. 2015 Jul;20(7):948-59. |