PeptideDB

(Rac)-Beraprost sodium

CAS: 88475-69-8 F: C24H29NaO5 W: 420.47

(Rac)-Beraprost ((Rac)-ML 1129) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orall
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Bioactivity (Rac)-Beraprost ((Rac)-ML 1129) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orally active prostacyclin analog that inhibits the release of Ca2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost sodium has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis[1][2].
CAS 88475-69-8
Formula C24H29NaO5
Molar Mass 420.47
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reference [1]. Li S, et al. Beraprost sodium mitigates renal interstitial fibrosis through repairing renal microvessels. J Mol Med (Berl). 2019 Jun;97(6):777-791. [2]. Yan P, et al. Clinical efficacy and safety of beraprost sodium in the treatment of nephrotic syndrome: A meta-analysis. Medicine (Baltimore). 2023 Oct 20;102(42):e34958.