Bioactivity | (RFR)4XB is a cationic membrane-penetrating peptide. (RFR)4XB carries its cargo (the antisense oligomer) across the outer membrane of gram-negative bacteria[1]. |
CAS | 1139931-15-9 |
Sequence | Arg-Phe-Arg-Arg-Phe-Arg-Arg-Phe-Arg-Arg-Phe-Arg-{Ahx}-{βAla} |
Shortening | RFRRFRRFRRFR-{Ahx}-{βAla} |
Formula | C93H150N38O15 |
Molar Mass | 2040.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mellbye BL, et al. Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. Antimicrob Agents Chemother. 2009 Feb;53(2):525-30. |