| Bioactivity | (R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1]. | ||||||||||||
| Name | (R,R)-CXCR2-IN-2 | ||||||||||||
| CAS | 1838123-22-0 | ||||||||||||
| Formula | C18H23ClN2O5S | ||||||||||||
| Molar Mass | 414.90 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Lu H, et al. Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists. J Med Chem. 2018;61(6):2518-2532. |
(R,R)-CXCR2-IN-2
CAS: 1838123-22-0 F: C18H23ClN2O5S W: 414.90
(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.