| Bioactivity | (R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R)-ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch[1]. | ||||||||||||
| Invitro | (R)-ZINC-3573 (0.001 nM-100 μM) 促进 β-己糖胺酶脱颗粒并诱导 LAD2 肥大细胞胞内钙释放[1]。 | ||||||||||||
| Name | (R)-ZINC-3573 | ||||||||||||
| CAS | 2089389-15-9 | ||||||||||||
| Formula | C18H21N5 | ||||||||||||
| Molar Mass | 307.39 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lansu K, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536. |
(R)-ZINC-3573
CAS: 2089389-15-9 F: C18H21N5 W: 307.39
(R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (
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