| Bioactivity | (R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence[1]. |
| Target | ED50: 0.21 mg/kg (prevented hypothalamic NE depletion) |
| Name | (R)-Thionisoxetine |
| CAS | 163059-33-4 |
| Formula | C17H21NOS |
| Molar Mass | 287.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gehlert DR, et al. (R)-thionisoxetine, a potent and selective inhibitor of central and peripheral norepinephrine uptake. Life Sci. 1995;56(22):1915-20. |
(R)-Thionisoxetine
CAS: 163059-33-4 F: C17H21NOS W: 287.42
(R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionis
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