| Bioactivity | (R)-SKBG-1 is an RNA-binding protein NONO inhibitor. (R)-SKBG-1 suppresses androgen receptor expression with IC50s of 3.1 μM and 5.5 μM against AR-FL mRNA and AR-V7 mRNA, respectively[1]. |
| Target | IC50: 3.1 μM (AR-FL mRNA), 5.5 μM (AR-V7 mRNA) |
| Name | (R)-SKBG-1 |
| Formula | C22H32ClN3O6S |
| Molar Mass | 502.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kathman SG, et al. Remodeling oncogenic transcriptomes by small molecules targeting NONO. Nat Chem Biol. 2023 Jul;19(7):825-836. |