Bioactivity | (R)-Nicardipine-d3 is the deuterium labeled R-Nicardipine (HY-12515C)[1]. | ||||||||||||
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 | ||||||||||||
Name | (R)-Nicardipine-d3 | ||||||||||||
Formula | C26H26D3N3O6 | ||||||||||||
Molar Mass | 482.54 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|
||||||||||||
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-235. |