Bioactivity | (R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1]. | ||||||||||||
Target | IC50: 8.4 nM (ACE2) | ||||||||||||
Invitro | (R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1]. | ||||||||||||
Name | (R)-MLN-4760 | ||||||||||||
CAS | 305335-29-9 | ||||||||||||
Formula | C19H23Cl2N3O4 | ||||||||||||
Molar Mass | 428.31 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Dales NA, et, al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc. 2002 Oct 9;124(40):11852-3. |