PeptideDB

(R)-MLN-4760

CAS: 305335-29-9 F: C19H23Cl2N3O4 W: 428.31

(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less acti
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Bioactivity (R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1].
Target IC50: 8.4 nM (ACE2)
Invitro (R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1].
Name (R)-MLN-4760
CAS 305335-29-9
Formula C19H23Cl2N3O4
Molar Mass 428.31
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Dales NA, et, al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc. 2002 Oct 9;124(40):11852-3.