Bioactivity | (R)-Ketoprofen is an orally active nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties. (R)-Ketoprofen does not significantly amplify the increase of inflammatory cytokines (such as tumor necrosis factor (TNF) and interleukin-1 (IL-1)) induced by LPS, but it can inhibit the anti-inflammatory activity of (S)-Ketoprofen[1][2]. |
CAS | 56105-81-8 |
Formula | C16H14O3 |
Molar Mass | 254.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Estrada-Valenzuela D, et al. Lipase Assisted (S)-Ketoprofen Resolution from Commercially Available Racemic Mixture. Pharmaceuticals (Basel). 2021 Sep 29;14(10):996. [2]. Ghezzi P, et al. Differential contribution of R and SIsomers in ketoprofen anti-inflammatory activity: role of cytokine modulation[J]. Journal of Pharmacology and Experimental Therapeutics, 1998, 287(3): 969-974. |