| Bioactivity | (R)-JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R)-JAK2/STAT3-IN-1 can inhibit the phosphorylation of JAK2 and STAT3. The affinity of (R)-JAK2/STAT3-IN-1 for GP130 protein is 3.8 μM. (R)-JAK2/STAT3-IN-1 effectively inhibits the viability and migration of tumor cells and promotes apoptosis[1]. |
| CAS | 2485758-49-2 |
| Formula | C34H35BrF3N5O2 |
| Molar Mass | 682.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Discovery of bazedoxifene analogues targeting glycoprotein 130 |
(R)-JAK2/STAT3-IN-1
CAS: 2485758-49-2 F: C34H35BrF3N5O2 W: 682.57
(R)-JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R)-JAK2/STAT3-IN-1 can inhibit the phospho
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