Bioactivity | (R)-FTY 720P is the R-isomer of FTY 720P. (R)-FTY 720P has less potent binding affinities to S1P1,3,4,5 than (S)-Isomer (HY-15382)[1]. |
In Vivo | (R)-FTY 720P (静脉推注给药) 对麻醉大鼠的心率在剂量达到 0.3mg/kg 时没有明显影响[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 402616-23-3 |
Formula | C19H34NO5P |
Molar Mass | 387.45 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kiuchi M, et al. Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate. Bioorg Med Chem. 2005 Jan 17;13(2):425-32. |