| Bioactivity | (R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor[1]. | ||||||||||||
| Invitro | (R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM[1]. | ||||||||||||
| Name | (R)-FT671 | ||||||||||||
| CAS | 1959551-27-9 | ||||||||||||
| Formula | C24H23F4N7O3 | ||||||||||||
| Molar Mass | 533.48 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486. |