| Bioactivity | (R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1]. | |||||||||
| Name | (R)-CE3F4 | |||||||||
| CAS | 1593478-56-8 | |||||||||
| Formula | C11H10Br2FNO | |||||||||
| Molar Mass | 351.01 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
|||||||||
| Reference | [1]. Courilleau D, et al. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8. |
(R)-CE3F4
CAS: 1593478-56-8 F: C11H10Br2FNO W: 351.01
(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.